An inhibitor of oxidosqualene cyclase (OSC) that has LDL cholesterol lowering activity inhibits OSC from human liver microsomes and HepG2 cells with IC50 values of approximately 6.5 and 1.5 nM, respectively.
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An inhibitor of oxidosqualene cyclase (OSC) that has LDL cholesterol lowering activity; inhibits OSC from human liver microsomes and HepG2 cells with IC50 values of approximately 6.5 and 1.5 nM, respectively.
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