RO8191 (C008B-270396)

RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC 50 of 200 nM for HCV replicon RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti- HBV activity .

Specifications & Purity: RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC 50 of 200 nM for HCV replicon RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti- HBV activity .

Grade: Moligand™

Molecular Formula: C14H5F6N5O

Molecular Weight: 373.21

EC Number: 809-506-3

PubChem CID: 2768133

Isomeric SMILES: C1=CC2=NC(=CN2C3=C1C(=CC(=N3)C(F)(F)F)C(F)(F)F)C4=NN=CO4

Storage Temperature: Store at -20°C;Argon charged

Shipped in: Ice chest + Ice pads

UPC:

42293414

Weight:

0.88 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

R648334-1g

Country of Origin:

China

CAS:

691868-88-9

Product Size:

1g

Harmonized Tariff Code:

2931.90.90

Health Hazards:

Toxic

Hazard Statement Codes:

H301

Precautionary Statement Codes:

P264;P270;P321;P330;P405;P501;P301+P316