RP-64477

RP-64477 RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.TargetsACAT (CaCo-2 cell-based assay); ACAT (THP-1 cell-based assay); ACAT (HepG2 cell-based assay) 113 nM; 180 nM; 503 nM

Acyltransferase Inhibitors

Specifications & Purity: RP-64477 RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT) . RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.TargetsACAT (CaCo-2 cell-based assay); ACAT (THP-1 cell-based assay); ACAT (HepG2 cell-based assay) 113 nM; 180 nM; 503 nM

Molecular Formula: C29H42N2O3S

Molecular Weight: 498.72

PubChem CID: 9870538

Isomeric SMILES: CCCCCCCCCCOC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C(=O)NCCCC)SC

Storage Temperature: Protected from light;Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/R412569-SCI_fc3a6cd85aed9445a1feac3e54a26226.pdf

UPC:

41113000

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

R412569-1mg

Country of Origin:

China

CAS:

135239-65-5

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H302;H315;H319;H335

Precautionary Statement Codes:

P261;P280;P301+P312;P302+P352;P305+P351+P338