SB220025 is a specific and potent human p38 mitogen-activated protein kinase. It has been shown to reduce the production of tumor necrosis factor induced by lipopolysaccharide. SB220025 has been found to reduce the expression of interleukin-1β and tumor necrosis factor-α and inhibit angiogenesis over the course of granuloma development. SB220025 has also been found to be capable of reducing inflammatory cytokine production, and thus could be a potential effective treatment for chronic proliferative inflammatory disease.
Specification: Moligand™, ≥95%
Molecular Formula: C18H19FN6
Molecular Weight: 338.38
PubChem CID: 5164
Isomeric SMILES: C1CNCCC1N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S339040-SCI_dd97b212b70a0bc827ff24fef1f804a2.pdf
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 4-8 weeks
- Weight:
- 0.07 Ounces
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- S339040-10mg
- CAS:
- 165806-53-1
- Health Hazards:
- Toxic
- Product Size:
- 10mg
- Hazard Statement Codes:
- H301:H335:H319:H315
- Precautionary Statement Codes:
- P501:P403+P233:P405:P362+P364:P305+P351+P338:P304+P340:P302+P352:P330:P280:P271:P270:P264:P261
