SB220025 (C007B-550908)

SB220025 is a specific and potent human p38 mitogen-activated protein kinase. It has been shown to reduce the production of tumor necrosis factor induced by lipopolysaccharide. SB220025 has been found to reduce the expression of interleukin-1β and tumor necrosis factor-α and inhibit angiogenesis over the course of granuloma development. SB220025 has also been found to be capable of reducing inflammatory cytokine production, and thus could be a potential effective treatment for chronic proliferative inflammatory disease.

Specification: Moligand™, ≥95%

Molecular Formula: C18H19FN6

Molecular Weight: 338.38

PubChem CID: 5164

Isomeric SMILES: C1CNCCC1N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S339040-SCI_dd97b212b70a0bc827ff24fef1f804a2.pdf

UPC:

12352200

Condition:

New

Weight:

0.07 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S339040-1mg

CAS:

165806-53-1

Health Hazards:

Toxic

Product Size:

1mg

Hazard Statement Codes:

H301:H335:H319:H315

Precautionary Statement Codes:

P501:P403+P233:P405:P362+P364:P305+P351+P338:P304+P340:P302+P352:P330:P280:P271:P270:P264:P261