SEN177 (C008B-270815)

SEN177 is a potent glutaminyl cyclase (QPCT) inhibitor with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). SEN177 has a K i of 20 nM for human glutaminyl cyclase (hQC). SEN177 greatly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates. SEN177 has the potential for Huntington’s disease research.Form:Solid

Specifications & Purity: SEN177 is a potent glutaminyl cyclase (QPCT) inhibitor with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). SEN177 has a K i of 20 nM for human glutaminyl cyclase (hQC). SEN177 greatly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates. SEN177 has the potential for Huntington’s disease research.Form:Solid

Grade: Moligand™

Molecular Formula: C18H19FN6

Molecular Weight: 338.38

EC Number: 821-054-9

PubChem CID: 91618245

Isomeric SMILES: CN1C=NN=C1C2CCN(CC2)C3=C(C=CC=N3)C4=CN=C(C=C4)F

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51442437

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S648491-100mg

Country of Origin:

China

CAS:

2117405-13-5

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90