Sigma-1 receptor antagonist 1 (C007B-417954)

Sigma‑1 receptor antagonist 1 (compound 137) is a potent and selective sigma-1 receptor (σ1R) antagonist, with a high binding affinity to σ1R receptor ( K i = 1.06 nM). Sigma‑1 receptor antagonist 1 exhibits antineuropathic pain activity and acts as a promising agent for the treatment of neuropathic painIn VitroSigma‑1 receptor antagonist 1 exhibits a high binding affinity to σ1R receptor (K i = 1.06 nM) and good σ-1/2 selectivity (1344-fold). MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoSigma‑1 receptor antagonist 1 exerts dose-dependent antinociceptive effects in mice formalin model and rats CCI models of neuropathic pain . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Sigma 1 Receptor. Specification: 0.99 Molecular Formula: C19H23Cl2N3O Molecular Weight: 380.31 PubChem CID: 101910737 Isomeric SMILES: CC1=C(C(=NC(=N1)C2=CC=C(C=C2)Cl)OCCCN3CCCCC3)Cl

UPC:

51371503

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S647431-50mg

CAS:

1639220-19-1

Product Size:

50mg