General description
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets.
Nitric oxide (NO) donor. Spontaneously decomposes to yield NO and superoxide anion radicals. Also inhibits the release of plasminogen activator inhibitor (PAI) from stimulated platelets. Unstable in aqueous solution.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Warning
Toxicity: Harmful (C)
Reconstitution
Unstable in aqueous solution; reconstitute just prior to use. Following reconstitution, aliquot and freeze (-20°C).
From Catalog:
Desc. Field- added "Unstable in aqueous solution."
Other Notes
Gow, A.J., et al. 2000. Am. J. Physiol. 278, C1099.
Gergel, D., et al. 1995. J. Biol. Chem.270, 20922.
de Groot, H., et al. 1993. FEBS Lett.315, 139.
Lipton, S.A., et al. 1993. Nature364, 626.
Drummer, C., et al. 1991. Thromb. Res.63, 553.
Omar, B.A., et al. 1990. Free Radical Biol. Med.9, 465
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
- UPC:
- 51123102
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 567028-20MG