SJB3-019A (C007B-418695)

SJB3-019A is a potent and novel USP1 inhibitor, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC 50 of 0.0781 μM.In VitroSJB3-019A (IC 50 =0.0781 μM) is 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells. SJB3-019A increases the levels of Ub-FANCD2 and Ub-PCNA, and decreases the HR activity. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 78.1 nM (ID1). Specification: 0.99 Molecular Formula: C16H8N2O3 Molecular Weight: 276.25 PubChem CID: 78358325 Isomeric SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C2=O)OC(=N3)C4=CN=CC=C4

UPC:

51313500

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S650665-50mg

CAS:

2070015-29-9

Product Size:

50mg