SKF 86002 (C008B-271787)

SKF 86002 is a bicyclic imidazole that specifically inhibits p38 MAP kinase, and is also described as a cytokine-suppressant and an anti-inflammatory compound. SKF 86002 has been shown to inhibit Cox (cyclooxygenase) activity and 5-LO (5-lipoxygenase). Osteoblastic cell studies report that SKF 86002 inhibits the production of IL-6. SKF 86002 has been shown to block the activation of TNF-translation and potently inhibit IL-1.

an inhibitor of p53, Cox, and 5-LO

Specifications & Purity: SKF 86002 is a bicyclic imidazole that specifically inhibits p38 MAP kinase, and is also described as a cytokine-suppressant and an anti-inflammatory compound. SKF 86002 has been shown to inhibit Cox (cyclooxygenase) activity and 5-LO (5-lipoxygenase). Osteoblastic cell studies report that SKF 86002 inhibits the production of IL-6. SKF 86002 has been shown to block the activation of TNF-translation and potently inhibit IL-1.

Grade: Moligand™

Molecular Formula: C16H12FN3S

Molecular Weight: 297.35

EC Number: 635-291-9

PubChem CID: 5228

Isomeric SMILES: C1CSC2=NC(=C(N21)C3=CC=NC=C3)C4=CC=C(C=C4)F

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S334616-SCI_fc81f2c39526017c5e99ffd19e700f31.pdf

UPC:

42293414

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S334616-25mg

Country of Origin:

China

CAS:

72873-74-6

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H315;H319;H335

Precautionary Statement Codes:

P261;P264;P271;P280;P321;P302+P352;P304+P340;P305+P351+P338;P362+P364;P405;P403+P233;P501;P264+P265;P337+P317;P332+P317;P319