SLF (C007B-418011)

SLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC 50 of 2.6 μM for FKBP12. SLF can be used in the synthesis of PROTAC .In VitroThree scout fragments-KB02, KB03, and KB05 are fused, which cover two different electrophile groups (chloroacetamide and acrylamide) and display broad cysteine reactivity in the human proteome-to the SLF ligand that binds tightly and selectively to FKBP12, a cytosolic prolyl isomerase that has been frequently used to study ligand-induced protein degradation. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Oil. Specification: 0.98 Molecular Formula: C30H40N2O6 Molecular Weight: 524.65 PubChem CID: 35027274 Isomeric SMILES: CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)N

UPC:

51111908

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S647692-5mg

CAS:

195513-96-3

Product Size:

5mg