General description
Sodium (meta)periodate is commonly used as an oxidizing agent in organic synthesis for the oxidation of various organic substrates. It can also be used as a co-oxidant with other oxidizing reagents such as osmium tetroxide and potassium permanganate. The oxidation of sodium periodate takes place in a water medium, but an organic co-solvent is used for organic substrates that are insoluble in water.
Application
Sodium (meta)periodate can be used as an oxidizing agent for the oxidation of:
- 1,2-diols to aldehydes or ketones via oxidative cleavage. Sulfides to sulfoxides in the presence of phase transfer catalysts.
- Diaryl, dialkyl, and aryl alkyl selenides to the respective selenoxides.
- Phenols and their derivatives to corresponding quinones.
- Acylphosphoranes to α,β-dicarbonyl compounds.
It can also be used in the:
- Selective alkene epoxidation and alkane hydroxylation,·
- Oxidation of carbohydrates.
- Iodination of aromatic compounds.
Useful reagent for the oxidation of carbohydrates prior to labeling with biotin hydrazide
Features and Benefits
NaIO4 is a stable, selective, and cost-effective reagent that is capable of reacting under mild conditions.
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- UPC:
- 41116104
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- MPN:
- S1878-25G
- CAS:
- 7790-28-5
