General description
Sry-related HMG-BOX gene 10, SOX-10, is a transcription factor involved in neural crest and peripheral nervous system development and acts as a nucleocytoplasmic shuttle protein. SOX-10 is expressed in melanocytic lineages and is a sensitive melanoma marker for conventional, and desmoplastic subtypes. In normal tissues, SOX-10 is expressed in melanocytes and myoepithelial cells.
Quality
IVD | IVD | IVD | RUO |
Linkage
SOX-10 Positive Control Slides, Product No. 383S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
Preparation Note
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
Other Notes
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
biological source: rabbit. Quality Level: 100, 500. conjugate: unconjugated. antibody form: culture supernatant. antibody product type: primary antibodies. clone: EP268, monoclonal. description: (For In Vitro Diagnostic Use in Select Regions (See Chart)). form: buffered aqueous solution. species reactivity: human. packaging: vial of 0.1 . mL concentrate (383R-14), vial of 0.5 . mL concentrate (383R-15), bottle of 1.0 . mL predilute (383R-17), vial of 1.0 . mL concentrate (383R-16), bottle of 7.0 . mL predilute (383R-18). manufacturer/tradename: Cell Marque™. . technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200. isotype: IgG. control: melanoma, skin melanocytes. shipped in: wet ice. storage temp.: 2-8°C. visualization: nuclear. Gene Information: human ... SOX10(6663).- UPC:
- 51142032
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- 383R-10