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Sigma-Aldrich

SR-301 (C005B-309745)

Biochem/physiol Actions SR-301 is an orally bioavailable analog of the selective STING agonist SR-717. SR-301 shows higher potency than SR-717 by THP1-based ISRE reporter assay (EC50 = 0.

Description

Biochem/physiol Actions

SR-301 is an orally bioavailable analog of the selective STING agonist SR-717. SR-301 shows higher potency than SR-717 by THP1-based ISRE reporter assay (EC50 = 0.6 vs. 2.1 μM, respectively) and shows good antitumor efficacy when administered orally in a murine B16.F10 melanoma tumor model in vivo (15 mg/kg/day p.o.).

Specifications
UPC:
51172305
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
5
Unit of Measurement:
MG
MPN:
SML2996-5MG
CAS:
2375419-35-3
Catalog No. C005B-309745
Price: $221.54
List Price: $246.15
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