Sigma-Aldrich
SR-4995 (C005B-311044)
Biochem/physiol Actions SR-4995 is a potent and selective ligand of α:-β:-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and
Description
Biochem/physiol Actions
SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling.
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Specifications
- UPC:
- 12352211
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- Yes
- Quantity:
- 5
- Unit of Measurement:
- MG
- MPN:
- SML2207-5MG
- CAS:
- 891509-95-8
- Controlled Substances and Cyanide:
- Yes
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