SR-717 lithium

SR-717 lithium SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.TargetsSTING (in ISG-THP1 (WT) cells); STING (in ISG-THP1 (cGAS KO) cells) 2.1 μM(EC50); 2.2 μM(EC50)

STING Agonists

Specifications & Purity: SR-717 lithium SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.TargetsSTING (in ISG-THP1 (WT) cells); STING (in ISG-THP1 (cGAS KO) cells) 2.1 μM(EC50); 2.2 μM(EC50)

Molecular Formula: C15H8F2LiN5O3

Molecular Weight: 351.19

PubChem CID: 139434658

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S412586-SCI_28943fc8750cd5e67041ebb7731a269a.pdf

UPC:

51442306

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

S412586-1mg

Country of Origin:

China

CAS:

2375421-09-1

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90

Hazard Statement Codes:

H302;H315;H319;H335

Precautionary Statement Codes:

P261;P305+P351+P338