Application
Succinyl coenzyme A sodium salt has been used:
- for the nonenzymatic succinylation of lysine in vitro,
- as a substrate for adipic acid biosynthesis in recombinant E. coli
- in isocitrate dehydrogenase (ICDH) treatment for the succinylation of proteins
- as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)
Biochem/physiol Actions
Succinyl CoA is an intermediate in the citric acid cycle. It is formed by α-ketoglutarate dehydrogenase by the decarboxylation of α-ketoglutarate. Succinyl CoA is also formed from propionyl CoA during the β-oxidation of odd-chain fatty acids. Succinyl CoA serves as a precursor in heme synthesis. It is also required for the oxidation of ketone bodies.
- UPC:
- 12352200
- Condition:
- New
- Availability:
- 3-5 Days
- Weight:
- 1.00 Ounces
- HazmatClass:
- No
- MPN:
- S1129-5MG
- CAS:
- 108347-97-3