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Sigma-Aldrich

SUCCINYL COENZYME A SODIUM SALT >=85% (C005B-377310)

Application Succinyl coenzyme A sodium salt has been used: for the nonenzymatic succinylation of lysine in vitro , as a substrate for adipic acid biosynthesis in recombinant E. coli in isocitrate dehydrogenase (ICDH) :treatment

Description

Application

Succinyl coenzyme A sodium salt has been used:

  • for the nonenzymatic succinylation of lysine in vitro,
  • as a substrate for adipic acid biosynthesis in recombinant E. coli
  • in isocitrate dehydrogenase (ICDH) treatment for the succinylation of proteins
  • as a substrate to study the specificity and kinetics of enzymes such as acetate:succinate CoA-transferase and 5-aminolevulinate synthase (ALA synthase)

Biochem/physiol Actions

Succinyl CoA is an intermediate in the citric acid cycle. It is formed by α-ketoglutarate dehydrogenase by the decarboxylation of α-ketoglutarate. Succinyl CoA is also formed from propionyl CoA during the β-oxidation of odd-chain fatty acids. Succinyl CoA serves as a precursor in heme synthesis. It is also required for the oxidation of ketone bodies.

Specifications
UPC:
12352200
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
25
Unit of Measurement:
MG
MPN:
S1129-25MG
CAS:
108347-97-3
Catalog No. C005B-377310
Price: $1,924.08
List Price: $2,137.86
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