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Sigma-Aldrich

SULBACTAM (C005B-342768)

General description Sulbactam is a semi-synthetic penicillinate sulfone derived from 6-aminopenicllanic acid. This β:-lactam compound is characterized by a β:-lactam ring.

Description

General description

Sulbactam is a semi-synthetic penicillinate sulfone derived from 6-aminopenicllanic acid. This β-lactam compound is characterized by a β-lactam ring.

Application

Sulbactam has been used as a β-Lactamase inhibitor in β-lactamase inhibitor assay. It has also been used to evaluate its antimicrobial pharmacodynamic effects against extremely drug-resistant Acinetobacter baumannii. Sulbactam may be used in cell signaling studies.

Biochem/physiol Actions

Sulbactam acts as an irreversible inhibitor of β-lactamases that inactivate β-lactams such as penicillin and cephalosporin. It is also active against bacteroides and certain chromosomally mediated enzymes of Gram-negative bacteria. It exhibits limited antimicrobial activity. However, sulbactam in combination with other potential antibiotics exhibits therapeutic effects against multidrug-resistant Acinetobacter baumannii infections.

Specifications
UPC:
51281708
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
10
Unit of Measurement:
MG
MPN:
S9701-10MG
CAS:
68373-14-8
Catalog No. C005B-342768
Price: $246.41
List Price: $273.79
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