TAK-683 acetate (C007B-431549)

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 values of 0.96 nM and 1.6 nM for humaAppearance:SolidIn Vitro:TAK-683 acetate exhibits an IC 50 value (95% CI) from receptor binding assays is 150-180 pM and EC 50 value (95% CI) from Ca + mobilization assays is 180 (159–203) pM in rat KISS1R-expressing Chinese hamster ovary (CHO) cells. MCE has not independentIn Vivo:TAK-683 acetate (subcutaneous injection; 0.008, 0.08, 0.8, or 8 μmol/ml/kg; once daily; 7 days) induces an increase in plasma luteinizing hormone and testosterone levels; however, after day 7, plasma hormone levels and genital organ weights are reduced.Biological Activity:TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist ( IC 50 =170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC 50 values of 0.96 nM and 1.6 nM for huma. Specification: 0.98 Molecular Formula: C66H87N17O15 Molecular Weight: 1358.5

UPC:

51181926

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No;ManufacturerName=Aladdin Scientific"

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T658894-1mg

Product Size:

1mg

Controlled Substances and Cyanide:

Yes