Taurolithocholic Acid(TLCA) (C007B-585786)

Taurolithocholic acid (TLCA) is a taurine-conjugated form of the secondary bile acid lithocholic acidTLCA (75 μM) increases caspase-3 and -7 activity in Hep3B cells transfected with sodium taurocholate cotransporting peptide (NTCP), but not nontransfected Hep3B cells.   It has been used to induce cholestasis in ex vivo and in vivo animal models of hepatocellular cholestasis.  Serum levels of TLCA increase approximately 5-fold within two hours during an oral lipid tolerance test in humans.

Specifictaions: Moligand™, ≥98%

MDL Number: C26H45NO5S

Molecular Formula: 483.70

PubChem CID: 439763

Isomeric SMILES: C[C@H](CCC(=O)NCCS(=O)(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C

UPC:

41115700

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T767008-1mg

CAS:

516-90-5

Product Size:

1mg