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ALADDIN SCIENTIFIC

TC-N 22A

TC-N 22A is a potent, selective, orally active and brain-permeable mGlu4 PAM with an EC50 of 9 nM in human mGlu4-expressing BHK cells. TC-N 22A is less active (EC50>10 μM) in agonist and PAM model at mGlu 1, 2, 3, 5, and 7 receptors.

Description

TC-N 22A is a potent, selective, orally active and brain-permeable mGlu4 PAM with an EC50 of 9 nM in human mGlu4-expressing BHK cells. TC-N 22A is less active (EC50>10 μM) in agonist and PAM model at mGlu 1, 2, 3, 5, and 7 receptors. TC-N 22A has the potential for research of CNS disease in vivo


Potent and selective positive allosteric modulator of mGlu4receptors


Specifications & Purity: TC-N 22A is a potent, selective, orally active and brain-permeable mGlu4 PAM with an EC50 of 9 nM in human mGlu4-expressing BHK cells. TC-N 22A is less active (EC50>10 μM) in agonist and PAM model at mGlu 1, 2, 3, 5, and 7 receptors. TC-N 22A has the potential for research of CNS disease in vivo


Grade: Moligand™


Molecular Formula: C14H13N5S


Molecular Weight: 283.35


PubChem CID: 46836562


Isomeric SMILES: C1CC2=C(C=NN2)C3=C(C1)SC(=N3)NC4=CC=CC=N4


Storage Temperature: Store at -20°C


Shipped in: Ice chest + Ice pads


More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T288621-SCI_47db86b62a128fe56ef3229b48f61c29.pdf


Specifications
UPC:
51442720
Weight:
1.06 Ounces
HazmatClass:
Yes
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
T288621-1mg
Country of Origin:
China
CAS:
1314140-00-5
Product Size:
1mg
Harmonized Tariff Code:
2931.90.90
Catalog No. C008B-274275
Price: $138.29
List Price: $153.65
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  • Shipping Lead-Time: 14-21 Days
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