Telomerase Inhibitor IX (C007B-440579)

Telomerase Inhibitor IX, also called MST-312, is a synthetic compound that acts as a reversible TERT (telomerase) inhibitor, and is described to be more potent than epigallocatechin gallate . UP37 cell studies suggest that in the presence of Telomerase Inhibitor IX, cell growth slows and the cells remain in the G|0|-G|1|cell cycle arrest. In addition, reports indicate that Telomerase Inhibitor IX does not inhibit|Taq|DNA polymerase .MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM)；:A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 µM). Specification: ≥98% Molecular Formula: C20H16N2O6 Molecular Weight: 380.35 PubChem CID: 10385095 Isomeric SMILES: C1=CC(=CC(=C1)NC(=O)C2=C(C(=CC=C2)O)O)NC(=O)C3=C(C(=CC=C3)O)O Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T342411-SCI_3a3fce7587d609895538e396bd86370c.pdf

UPC:

51111757

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T342411-25mg

CAS:

368449-04-1

Product Size:

25mg

Hazard Statement Codes:

H400

Precautionary Statement Codes:

P501:P391:P273