Tigecycline tetramesylate (C007B-431597)

Tigecycline tetramesylate (GAR-936 tetramesylate) is a broad-spectrum glycylcycline antibiotic . The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL. MIC 50 and MIC 90 are 1 and 2 mg/L for AciAppearance:SolidIC50& Target:Mean MIC: 125 ng/mL ( E. coli ) MIC50: 1 mg/mL ( A. baumannii ) MIC90: 2 mg/mL ( A. baumannii )In Vitro:Tigecycline (0.63-30 µM, preincubated for 4 days, treated for 72 h) inhibits AML2 cells and HL-60 cells with IC 50 s of 4.72±0.54 and 3.06±0.85 μM (freshly prepared). Tigecycline inhibits AML2 cells and HL-60 cells with IC 50 s of 5.64±0.55 and 4.27±0.45In Vivo:Tigecycline (50mg/kg; intraperitoneal injection; twice a day; for 11 days) reduces tumor volume and weight in NOD/SCID mice. The peak plasma concentration (C max ), the terminal half-life (t 1/2 ), area under the plasma concentration-time curve (AUCBiological Activity:Tigecycline tetramesylate (GAR-936 tetramesylate) is a broad-spectrum glycylcycline antibiotic . The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL. MIC 50 and MIC 90 are 1 and 2 mg/L for Aci. Specification: ≥95% Molecular Formula: C33H55N5O20S4 Molecular Weight: 970.07

UPC:

51282003

Condition:

New

Weight:

1.09 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T659191-10mg

Product Size:

10mg