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tmx-201 (c09-1183-475)

TMX-201 (C09-1183-475)

Aladdin

Catalog No.
C09-1183-475
Manufacturer No.
T655723-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA
Price: $1,045.16
List Price: $1,161.29

TMX-201 is a TLR7 ligand-phospholipid conjugate. TMX-201 shows potent immune stimulatory activity. TMX-201 can be used for breast cancer and melanoma researchIn VitroTMX-201 is more potent cytokine inducer than Imiquimod (HY-B0180) in both mouse and

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TMX-201 is a TLR7 ligand-phospholipid conjugate. TMX-201 shows potent immune stimulatory activity. TMX-201 can be used for breast cancer and melanoma researchIn VitroTMX-201 is more potent cytokine inducer than Imiquimod (HY-B0180) in both mouse and human mononuclear cells. TMX-201 shows less off-target binding compared to Imiquimod. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoThe maximum tolerated dose of TMX-201 by i.v. administration is 75 mg/kg . TMX-201 (4mg/kg, IP) suppresses the growth of established subcutaneous B16 melanoma by 46%, without discernible adverse effects . TMX-201 (IP or intra-tumor administration), in combination with anti-CTLA4 antibody, significantly suppressed lung metastasis formation in the 4T1 breast cancer model . MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:TLR7. Specifications and Purity: 10mM in DMSO. Molecular Formula: C57H93N6O12P. Molecular Weight: 1085.36.
UPC:
12352005
Condition:
New
Availability:
8-12 weeks
Weight:
1.06 Ounces
HazmatClass:
No
WeightUOM:
LB
MPN:
T655723-1ml
CAS:
1149339-78-5
Product Size:
1ml


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