Toddaculin (C008B-271183)

Toddaculin is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity .In VitroToddaculin (5-250 μM; 24-72 h) shows anti-proliferative activity in U-937 cells, with an IC 50 of 51.38 μM. Toddaculin (25-250 μM; 24-48 h) induces partial differentiation in U-937 leukemic cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid

Phenylpropanoids Coumarins

Specifications & Purity: Toddaculin is a natural coumarin that can induce differentiation and apoptosis in leukemic cells. Toddaculin suppresses excess osteoclast activity and enhances osteoblast differentiation and mineralization. Toddaculin also exhibits anti-inflammatory activity .In VitroToddaculin (5-250 μM; 24-72 h) shows anti-proliferative activity in U-937 cells, with an IC 50 of 51.38 μM. Toddaculin (25-250 μM; 24-48 h) induces partial differentiation in U-937 leukemic cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid

Grade: Moligand™

Molecular Formula: C16H18O4

Molecular Weight: 274.31

PubChem CID: 5321960

Isomeric SMILES: CC(=CCC1=C(C=C2C(=C1OC)C=CC(=O)O2)OC)C

Storage Temperature: Store at 2-8°C;Protected from light;Desiccated

Shipped in: Wet ice

UPC:

51111908

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T648055-25mg

Country of Origin:

China

CAS:

4335-12-0

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90