TPBM

TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC50 value of 9 μM for 17β-estradiol (E2)-ERα. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC50=5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth.

a potent inhibitor of estrogen receptor α

Specifications & Purity: TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC50 value of 9 μM for 17β-estradiol (E2)-ERα. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC50=5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth.

Molecular Formula: C15H16N4O2S

Molecular Weight: 316.38

PubChem CID: 262425

Isomeric SMILES: CN1C2=C(C(=O)N(C1=O)C)NC(=N2)CSCC3=CC=CC=C3

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T345098-SCI_3c1c46a476a967057a03f316abfeca65.pdf

UPC:

42203606

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T345098-1mg

Country of Origin:

China

CAS:

6466-43-9

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90

Precautionary Statement Codes:

P264