TRAP-6 (C007B-430798)

TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor . TRAP-6 shows no activity at PAR4In VitroTRAP-6 (0.01-10 μM) triggers calcium mobilization in Xenopus oocytes heterologously expressing PAR1. TRAP-6 (0.01-10 μM; 30 min) activates human platelets. TRAP-6 (100 μM) does not cause the platelets of rabbits or rats to change shape, aggregate, release granule contents, or form thromboxane. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoTRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:PAR1. Specification: 0.99 Molecular Formula: C34H56N10O9 Molecular Weight: 748.88 PubChem CID: 9831933 Isomeric SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(=O)N)C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)N

UPC:

51183309

Condition:

New

Weight:

1.06 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T649035-10mg

CAS:

141136-83-6

Product Size:

10mg