Tri(1-aziridinyl)phosphine sulfide (C007B-281140)

The unstable nitrogen-carbon groups alkylate with DNA which causes irreversible DNA damage. They stop tumor growth by crosslinking guanine nucleobases in DNA double-helix strands, directly attacking DNA. The DNA strands are unable to uncoil and separate which halts cell division.Thio-TEPA (N,N’N’-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and bladder cancer. It is also used as conditioning treatment prior to haematopoietic progenitor cell transplantation (HPCT). Specification: 0.98 MDL Number: MFCD00145452 Molecular Formula: C6H12N3PS Molecular Weight: 189.22 EC Number: 200-135-7 PubChem CID: 5453 Isomeric SMILES: C1CN1P(=S)(N2CC2)N3CC3 Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/T123963-SCI_8da847f0d948d10452e8974564638387.pdf

UPC:

51284046

Condition:

New

Weight:

0.88 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

T123963-1g

CAS:

52-24-4

Health Hazards:

Toxic

Product Size:

1g

Hazard Statement Codes:

H300:H350

Precautionary Statement Codes:

P201:P264:P301+P310:P308+P313