TRIMETHYLTIN CHLORIDE (C005B-005959)

General description

Trimethyltin chloride is an organotin reagent widely used in transferring trimethylstannyl groups onto the substrates to synthesize various organostannanes. Trimethylstannyl compounds derived from this reagent, are extensively used in the palladium-catalyzed Stille coupling reactions.

Application

Trimethyltin chloride can be used as a precursor to synthesize trimethyltin hydride, cyanide, methoxide, azide, and lithium compounds.
It can also be used as a reagent to prepare:

• Organotrimethyltin derivatives by reacting with organocopper compounds via transmetalation reaction.
• Acetophenone by palladium-catalyzed coupling reaction with benzoyl chloride.
• Optically active propargyl trimethylstannane by treating with chiral allenyltitanium.
• Trimethylstannyl nucleophiles, which are applicable in the formation of Sn-C bonds via SN2 reactions, SRN1 reactions, and halogen-metal exchanges.
• Carbocycles by reacting with unactivated dienes or trienes via radical-mediated carbocyclization reaction in the presence of NaBH₃CN and a catalytic amount of AIBN.

UPC:

12352103

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

Yes

Quantity:

10

Unit of Measurement:

GR

MPN:

146498-10G

CAS:

1066-45-1

Temperature Control Device:

Yes

Controlled Substances and Cyanide:

Yes