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ALADDIN SCIENTIFIC

ULK-101

ULK-101 ULK-101 is a potent and selective ULK1 inhibitor with IC50 values of 8.3 nM and 30 nM for ULK1 and ULK2, respectively.

Description

ULK-101 ULK-101 is a potent and selective ULK1 inhibitor with IC50 values of 8.3 nM and 30 nM for ULK1 and ULK2, respectively.TargetsULK1 (Cell-free assay); ULK2 (Cell-free assay) 8.3 nM; 30 nMIn vitroULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli. ULK-101 sensitizes KRAS mutant lung cancer cells to nutrient stress.Cell Research(from reference)Cell lines:U2OS cells Concentrations:5 μM Incubation Time:2.5 h


ULK Inhibitors


Specifications & Purity: ULK-101 ULK-101 is a potent and selective ULK1 inhibitor with IC50 values of 8.3 nM and 30 nM for ULK1 and ULK2, respectively.TargetsULK1 (Cell-free assay); ULK2 (Cell-free assay) 8.3 nM; 30 nMIn vitroULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli. ULK-101 sensitizes KRAS mutant lung cancer cells to nutrient stress.Cell Research(from reference)Cell lines:U2OS cells Concentrations:5 μM Incubation Time:2.5 h


Molecular Formula: C22H16F4N4OS


Molecular Weight: 460.45


PubChem CID: 137628686


Isomeric SMILES: C1CC1[C@@H](C(F)(F)F)NC(=O)C2=CC(=CS2)C3=C4N=CC(=CN4N=C3)C5=CC=C(C=C5)F


Storage Temperature: Store at -20°C


Shipped in: Ice chest + Ice pads


More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/U414186-SCI_d5b4f63d4f86a2bef91fad8143de067a.pdf


Specifications
UPC:
51442306
Weight:
1.06 Ounces
HazmatClass:
Yes
Quantity:
1
Unit of Measurement:
EA
WeightUOM:
LB
MPN:
U414186-1mg
Country of Origin:
China
CAS:
2443816-45-1
Product Size:
1mg
Harmonized Tariff Code:
2931.90.90
Catalog No. C008B-274395
Price: $114.06
List Price: $126.73
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  • Shipping Lead-Time: 14-21 Days
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