UNC1062

UNC1062 is a MERTK -selective tyrosine kinase inhibitor, reduces activation of MERTK-mediated downstream signaling, induces apoptosis in culture, reduces colony formation in soft agar, and inhibits invasion of melanoma cells. UNC1062 potently inhibits MERTK kinase activity (MERTK IC 50 =1.1 nM, Morrison K i =0.33 nM) and exhibits specificity within the TAM family (TYRO3 IC 50 =60 nM, AXL IC 50 =85 nM).Form:Solid

Specifications & Purity: UNC1062 is a MERTK -selective tyrosine kinase inhibitor, reduces activation of MERTK-mediated downstream signaling, induces apoptosis in culture, reduces colony formation in soft agar, and inhibits invasion of melanoma cells. UNC1062 potently inhibits MERTK kinase activity (MERTK IC 50 =1.1 nM, Morrison K i =0.33 nM) and exhibits specificity within the TAM family (TYRO3 IC 50 =60 nM, AXL IC 50 =85 nM).Form:Solid

Grade: Moligand™

Molecular Formula: C25H34N6O4S

Molecular Weight: 514.64

PubChem CID: 68212798

Isomeric SMILES: CCCCNC1=NC=C2C(=NN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)S(=O)(=O)N5CCOCC5

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51442306

Weight:

1.09 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

U650870-100mg

Country of Origin:

China

CAS:

1350549-36-8

Product Size:

100mg

Harmonized Tariff Code:

2931.90.90