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Sigma-Aldrich

VALRUBICIN (C005B-475079)

Biochem/physiol Actions Valrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. Valrubicin is converted intracytoplasmically into N-trifluoroacetyladriamycin, which interacts with topoisomerase II,

Description

Biochem/physiol Actions

Valrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. Valrubicin is converted intracytoplasmically into N-trifluoroacetyladriamycin, which interacts with topoisomerase II, stabilizing the complex between the enzyme and DNA and causing cell cycle arrest.

Specifications
UPC:
51281810
Condition:
New
Weight:
1.00 Ounces
HazmatClass:
No
Quantity:
20
Unit of Measurement:
MG
MPN:
SML2516-20MG
CAS:
56124-62-0
Catalog No. C005B-475079
Price: $562.75
List Price: $625.28
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