WM-8014 (C007B-308785)

InformationWM-8014 WM-8014 is a highly potent inhibitor of histone acetyltransferase KAT6A with an IC50 of 8 nM.TargetsKAT6A (Cell-free assay) 8 nMIn vitroWM-8014 induces cell cycle arrest in embryonic day (E)14.5 mouse embryonic fibroblasts.Cells treated with WM-8014 failed to proliferate after ten days of treatment (IC50 2.4 μM). Higher doses of WM-8014 (up to 40 μM) did not accelerate growth arrest, which after eight days of treatment was irreversible.In vivoWM-8014 potentiates oncogene-induced senescence in a zebrafish model of hepatocellular carcinoma. Specification: 0.99 Molecular Formula: C20H17FN2O3S Molecular Weight: 384.42 PubChem CID: 133053564 Isomeric SMILES: CC1=CC(=CC(=C1F)C(=O)NNS(=O)(=O)C2=CC=CC=C2)C3=CC=CC=C3

UPC:

41115310

Condition:

New

Weight:

0.97 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

W413571-100mg

CAS:

2055397-18-5

Product Size:

100mg