XANTHINE OXIDASE FROM BOVINE MILK GRADE IV AMMONIUM SULFATE SUSPENSION >= 0.1 UNITS/MG PROTEIN (C005B-275383)

General description

Formerly E.C. 1.1.3.22

Biochem/physiol Actions

Although xanthine oxidase is found widely distributed in multiple tissues, it is highly expressed in endothelial and epithelial cells. Its expression was also increased in infected tissues where it was shown to have an anti-microbial effect due to its ability to generate reactive oxygen species.

Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.

Unit Definition

One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.

Physical form

Suspension in 2.3 M (NH₄)₂SO₄ containing 1 mM sodium salicylate

Analysis Note

Protein determined by biuret

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UPC:

41115406

Condition:

New

Weight:

1.00 Ounces

HazmatClass:

No

Quantity:

40

Unit of Measurement:

UN

MPN:

X4875-40UN

CAS:

9002-17-9

Temperature Control Device:

Yes