Y 134

Y134 is an estrogen receptor inhibitor that is selective and orally active, exhibiting strong antagonist activity against ERα and Erβ with Ki of 0.09 nM and 11.31 nM, respectively. The selectivity of Y134 for ERα is 121.1 times higher than that for ERβ. Y134 inhibited the proliferation of ER positive human breast cancer cells stimulated by estrogen.

Selective estrogen receptor modulator (SERM), selective for ERα

Specifications & Purity: Y134 is an estrogen receptor inhibitor that is selective and orally active, exhibiting strong antagonist activity against ERα and Erβ with Ki of 0.09 nM and 11.31 nM, respectively. The selectivity of Y134 for ERα is 121.1 times higher than that for ERβ. Y134 inhibited the proliferation of ER positive human breast cancer cells stimulated by estrogen.

Grade: Moligand™

Molecular Formula: C₂₈H₂₈N₂O₃S

Molecular Weight: 472.6

PubChem CID: 11784736

Isomeric SMILES: CC(C)N1CCN(CC1)C2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O

Storage Temperature: Store at -20°C;Desiccated

Shipped in: Ice chest + Ice pads

More Information: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/Y286556-SCI_8a88f9a2f3c6f74005a5b39b96ae71a8.pdf

UPC:

41113000

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

Y286556-1mg

Country of Origin:

China

CAS:

849662-80-2

Product Size:

1mg

Harmonized Tariff Code:

2931.90.90

Precautionary Statement Codes:

P264