YKL-5-124 (C008B-268009)

YKL-5-124 is a potent, selective and covalentCDK7inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for inhibiting CDK7/Mat1/CycH, CDK2 and CDK9 respectively. It displays biochemical and cellular selectivity for CDK7 over CDK12/13.TargetsCDK7 (Cell-free assay) 9.7 nM

CDK7 Selective Inhibitors

Specifications & Purity: YKL-5-124 is a potent, selective and covalentCDK7inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for inhibiting CDK7/Mat1/CycH, CDK2 and CDK9 respectively. It displays biochemical and cellular selectivity for CDK7 over CDK12/13.TargetsCDK7 (Cell-free assay) 9.7 nM

Grade: Moligand™

Molecular Formula: C28H33N7O3

Molecular Weight: 515.61

PubChem CID: 121443990

Isomeric SMILES: CC1(C2=C(CN1C(=O)N[C@H](CN(C)C)C3=CC=CC=C3)C(=NN2)NC(=O)C4=CC=C(C=C4)NC(=O)C=C)C

Storage Temperature: Protected from light;Store at -20°C;Argon charged

Shipped in: Ice chest + Ice pads

UPC:

51432313

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

Y414229-25mg

Country of Origin:

China

CAS:

1957203-01-8

Product Size:

25mg

Harmonized Tariff Code:

2931.90.90