Zamicastat (C008B-267184)

Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) that could cross the blood-brain barrier (BBB) and cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 of 73.8 μM and 17.0 μM, respectively. Zamicastat reduces high blood pressure.

Specifications & Purity: Zamicastat (BIA 5-1058) is an inhibitor of dopamine β-hydroxylase (DBH) that could cross the blood-brain barrier (BBB) and cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 of 73.8 μM and 17.0 μM, respectively. Zamicastat reduces high blood pressure.

Grade: Moligand™

Molecular Formula: C21H21F2N3OS

Molecular Weight: 401.5

PubChem CID: 25052630

Isomeric SMILES: C1[C@H](COC2=C1C=C(C=C2F)F)N3C(=CNC3=S)CCNCC4=CC=CC=C4

Storage Temperature: Store at -20°C

Shipped in: Ice chest + Ice pads

UPC:

51361704

Weight:

1.06 Ounces

HazmatClass:

Yes

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

Z412408-50mg

Country of Origin:

China

CAS:

1080028-80-3

Product Size:

50mg

Harmonized Tariff Code:

2931.90.90