CAYMAN CHEMICAL
Zaragozic Acid A-5 mg
A reversible competitive inhibitor of squalene synthase (Ki = 78 pM in vitro) reduces cholesterol synthesis in HepG2 cells (IC50 = 6 µM) and inhibits hepatic cholesterol synthesis in mice (ED50 = 0.2 mg/kg) also
Description
A reversible competitive inhibitor of squalene synthase (Ki = 78 pM in vitro); reduces cholesterol synthesis in HepG2 cells (IC50 = 6 µM) and inhibits hepatic cholesterol synthesis in mice (ED50 = 0.2 mg/kg); also inhibits FPTase and GGPTase-I (IC50s = 216 and 50 nM, respectively).
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Specifications
- UPC:
- 51321500
- Condition:
- New
- Weight:
- 1.00 Ounces
- HazmatClass:
- No"
- WeightUOM:
- LB
- MPN:
- 17452-5
- Model Number:
- C816R44
- Temperature Control Device:
- Yes
Catalog No.
C003B-121130
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