Aladdin-1

P282897 is recommended for use in hydrogenation reactions for the partial reduction of functional groups. Specifically, it is suited for the selective hydrogenation of alkynes to alkenes where a high selectivity towards the cis-alkene is being...

Palifosfamide

PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute...

PSI-6130 is a potent and selective inhibitor of HCV NS5B polymerase.

PQCA is a highly selective and potent muscarinic M1 receptor positive allosteric modulator. PQCA has an EC 50 value of 49 nM and 135 nM on rhesus and human M1 receptor , respectively.

Potent inhibitor of Abl T315l mutant and wild-type Abl kinases

PPADS Tetrasodium is an non-selective purinergic antagonists of P2 ATP receptors. PPADS Tetrasodium is also a potential neuroprotective agents for the treatment of autoimmune and demyelinating disease.

Carboxylic acid poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a carboxylic acid-functionalized, biocompatible, amphiphilic blockcopolymer. Due to its self-assembling properties, this material can be used in the formation of...

Selective α7 nAChR agonist

Potent and selective Nav1.7 channel blocker

PF-04971729(Ertugliflozin) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2(SGLT2).Ertugliflozin (MK-8835, PF-04971729) is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50...

PF-00835231 PF-00835231 is a 3CL pro (M pro ) inhibitor that may targets SARS-CoV-2 protease 3CL pro as a potential new treatment for COVID-19.Targets3CLproIn vitroA time-of-drug-addition approach delineates the timing of early SARS-CoV-2 life...