Aladdin-1

SR11237 may be used in RXR-mediated cell signaling studies. Pan RXR agonist

Potent RET inhibitor

The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8.

SP-96 is a potent, selective and non-ATP-competitive inhibitor ofAurora Bwith IC50 of 0.316 nM.

NF-κB and AP-1 dual inhibitor

SNDX-5613 SNDX-5613 is a potent and selective inhibitor of menin-MLL binding with a Ki of 0.15 nM.

SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan.

IFN Activators

SM(PEG)n NHS- and maleimide-activated PEG compounds for crosslinking between primary amines (NH2) and sulfhydryl (SH) groups in proteins and other molecules. A complete set of compounds are offered, each having the same heterobifunctional...

SM(PEG)12

SKF 86466 hydrochloride is a novel selective alpha-2 adrenergic receptor antagonist. Benalfocin reduces blood pressure and heart rate.

Plasminogen activator inhibitor-1 (PAI-1) inhibitor