Ceritinib dihydrochloride (C007B-102667)

InformationCeritinib dihydrochloride Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR , IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.TargetsALK (Cell-free assay); InsR (Cell-free assay); IGF-1R (Cell-free assay); STK22D (Cell-free assay);0.2 nM; 7 nM; 8 nM; 23 nM. Specification: 10mM in DMSO Molecular Formula: C28H38Cl3N5O3S Molecular Weight: 631.06 PubChem CID: 67973512 Isomeric SMILES: CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl.Cl.Cl

UPC:

51112020

Condition:

New

Weight:

0.85 Ounces

HazmatClass:

No

Quantity:

1

Unit of Measurement:

EA

WeightUOM:

LB

MPN:

C421439-1ml

CAS:

1380575-43-8

Product Size:

1ml