Immunology

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four

Histone H2A is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H2A is involved with the structure of the nucleosomes of the &#8242beads on a

H2AX comprises 2-25% of the total H2A complement in human cells, whereas in the budding yeast it constitutes virtually all of the H2A molecules. It has N-terminal and C-terminal region with a central globular domain.

Immunogen KLH-conjugated peptide (ARK[pS]TGGKAPRKQL- C) corresponding to amino acids 7-20 of human histone H3. Application Anti-phospho-Histone H3 (Ser10) Antibody, biotin conjugate is a Rabbit Polyclonal Antibody for detection of Histone H3

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the &#8242beads on

ILK (Integrin-Linked Kinase) is an intraceullar Ser/Thr kinase with four Ankyrin-like repeats. It is known to play pivotal roles in extracellular matrix mediated signaling.

Specificity Integrin B1 phosphorylated on Ser785 Immunogen C-terminal Peptide Application Detect phospho-Integrin &#9461 (Ser785) using this Anti-phospho-Integrin &#9461 (Ser785) Antibody validated for use in WB. Research Category Cell Structure

Keratin, type II cytoskeletal 8 (UniProt P05787 also known as CK-8, Cytokeratin-8, K8, Keratin-8, Type-II keratin Kb8) is encoded by the KRT8 (also known as CYK8) gene (Gene ID 3856) in human. Cytokeratin-8 (Keratin-8 or K8) belongs to a family of

Dual specificity mitogen-activated protein kinase kinase 7 (UniProt: O14733 also known as EC:2.7.

Mixed lineage kinase domain-like protein (MLKL) is required for the execution of programmed necrosis. MLKL is a cell-permeable acrylamide compound that inhibits human, but not murine, MLKL adaptor function via covalent modification of Cys86.

Specificity Munc-18, phospho Serine 515. The antibody recognizes a protein of ~65 kDa corresponding to Munc-18, phospho Serine 515 in lysates from rat cortex.

Specificity Recombinant truncated chicken MYPT1 phosphorylated on Thr850. Immunogen Peptide corresponding to amino acid residues 845-855 of chicken MYPT1 this sequence is identical to amino acids 848-858 of human MYPT1, with the phosphorylated Thr