Protection/Deprotection Reagents

Ethylene glycol polymer-bound.

DescriptionPowerful guanidinylation reagent from theBaran Lab developed for the installation of monoprotected boc-guanidine on primary and secondary amines, particularly electron-deficient andhindered amines.

DescriptionThis compound undergoes cycloreversion to form the fluoro(hetero)aryl ketene, which undergoes efficient coupling with nucleophiles and allows rapid incorporation of highly fluorinated α-fluoro(hetero)aryl acetic acid derivatives.

Reacta-Sil™.

DescriptionTBAF(9-Ph-9-fluorenol)3is a fluoride–alcohol complex. It is formed by reacting 9-phenylfluoren-9-ol with tetrabutylammonium fluoride trihydrate (TBAF(H2O)3). The geometric structure and bonding of TBAF(9-Ph-9-fluorenol)3have been

DescriptionTBAF(pin)2is a fluoride–alcohol complex with coordination number four. It can be obtained by reacting pinacol (pin) with tetrabutylammonium fluoride trihydrate (TBAF(H2O)3). The geometric structure and bonding of TBAF(pin)2have been

DescriptionNucleophilic fluorinating reagent is a more convenient crystalline solid for handling and storage compared to tetrabutylammonium fluoride hydrate (Aldrich 241512). As reported by Engle and Gouverneur, these solids display comparable

Versatile protecting reagent for amines, amides, and especially alcohols, among others.Can be selectively removed in the presence of a t-BuPh2Si-protected alcohol.Used in a preparatrion of isoxazoline N-oxides from α-bromonitroalkanes.

Versatile protecting reagent for amines, amides, and especially alcohols, among others.Can be selectively removed in the presence of a t-BuPh2Si-protected alcohol.Used in a preparatrion of isoxazoline N-oxides from α-bromonitroalkanes.

tert-Butyldimethylsilyl chloride solution.